{"product_id":"larazotide-acetate-250mcg-x-60caps-research-only","title":"Larazotide Acetate 250mcg x 60caps : Research Only","description":"\u003cdiv class=\"Y3BBE\" data-sfc-cp=\"\" data-hveid=\"CAMQAA\" data-processed=\"true\"\u003eLarazotide acetate is a synthetic, eight-amino-acid peptide that was developed to function as a tight junction regulator. In celiac disease, the ingestion of gluten can lead to an inflammatory response that opens the \"tight junctions\"—the connections between the cells of the intestinal lining. This allows more gluten fragments to pass into the gut lining, which perpetuates the inflammation.\u003cspan class=\"uJ19be notranslate\" data-wiz-uids=\"EOOE2c_n,EOOE2c_o,EOOE2c_p\" data-processed=\"true\"\u003e\u003cspan class=\"vKEkVd\" data-animation-atomic=\"\" data-processed=\"true\"\u003e \u003cbutton data-amic=\"true\" data-icl-uuid=\"34163c97-07e7-449b-9473-3139f688d6ad\" aria-label=\"View related links\" class=\"rBl3me\" data-wiz-attrbind=\"disabled=EOOE2c_n_C5gNJc;class=EOOE2c_n_UpSNec;\" data-ved=\"2ahUKEwjSwM-l1ZWRAxXcTEEAHcQ1MEQQye0OegQIAxAB\" data-processed=\"true\" tabindex=\"0\"\u003e\u003cspan class=\"wiMplc ofC0Ud\" data-processed=\"true\"\u003e\u003csvg fill=\"currentColor\" width=\"12px\" height=\"12px\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M3.9 12c0-1.71 1.39-3.1 3.1-3.1h4V7H7c-2.76 0-5 2.24-5 5s2.24 5 5 5h4v-1.9H7c-1.71 0-3.1-1.39-3.1-3.1zM8 13h8v-2H8v2zm9-6h-4v1.9h4c1.71 0 3.1 1.39 3.1 3.1s-1.39 3.1-3.1 3.1h-4V17h4c2.76 0 5-2.24 5-5s-2.24-5-5-5z\"\u003e\u003c\/path\u003e\u003c\/svg\u003e\u003c\/span\u003e\u003c\/button\u003e\u003c\/span\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"Y3BBE\" data-sfc-cp=\"\" data-hveid=\"CAQQAA\" data-processed=\"true\"\u003eLarazotide acetate is designed to remain in the gut and is not significantly absorbed into the bloodstream. It works by acting as a zonulin antagonist, blocking the process that causes these tight junctions to open.\u003cspan class=\"uJ19be notranslate\" data-wiz-uids=\"EOOE2c_s,EOOE2c_t,EOOE2c_u\" data-processed=\"true\"\u003e\u003cspan class=\"vKEkVd\" data-animation-atomic=\"\" data-processed=\"true\"\u003e \u003cbutton data-amic=\"true\" data-icl-uuid=\"a4180269-1e8b-40ee-94a9-d80cddff7171\" aria-label=\"View related links\" class=\"rBl3me\" data-wiz-attrbind=\"disabled=EOOE2c_s_C5gNJc;class=EOOE2c_s_UpSNec;\" data-ved=\"2ahUKEwjSwM-l1ZWRAxXcTEEAHcQ1MEQQye0OegQIBBAB\" data-processed=\"true\" tabindex=\"0\"\u003e\u003cspan class=\"wiMplc ofC0Ud\" data-processed=\"true\"\u003e\u003csvg fill=\"currentColor\" width=\"12px\" height=\"12px\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 24 24\"\u003e\u003cpath d=\"M3.9 12c0-1.71 1.39-3.1 3.1-3.1h4V7H7c-2.76 0-5 2.24-5 5s2.24 5 5 5h4v-1.9H7c-1.71 0-3.1-1.39-3.1-3.1zM8 13h8v-2H8v2zm9-6h-4v1.9h4c1.71 0 3.1 1.39 3.1 3.1s-1.39 3.1-3.1 3.1h-4V17h4c2.76 0 5-2.24 5-5s-2.24-5-5-5z\"\u003e\u003c\/path\u003e\u003c\/svg\u003e\u003c\/span\u003e\u003c\/button\u003e\u003c\/span\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cul class=\"KsbFXc U6u95\" data-processed=\"true\"\u003e\n\u003cli data-hveid=\"CAcQAA\" data-processed=\"true\"\u003e\u003cspan class=\"T286Pc\" data-sfc-cp=\"\" data-processed=\"true\"\u003e\u003cstrong class=\"Yjhzub\" data-processed=\"true\"\u003eReduced gastrointestinal symptoms:\u003c\/strong\u003e In Phase 2 trials, patients with celiac disease who were following a gluten-free diet but still experiencing symptoms reported a significant reduction in discomfort, abdominal pain, and fatigue when taking a specific low dose \u003c\/span\u003e\u003c\/li\u003e\n\u003cli data-hveid=\"CAcQAQ\" data-processed=\"true\"\u003e\u003cspan class=\"T286Pc\" data-sfc-cp=\"\" data-processed=\"true\"\u003e\u003cstrong class=\"Yjhzub\" data-processed=\"true\"\u003eBlocked immune response:\u003c\/strong\u003e Some studies showed that the drug could reduce the gluten-induced immune reaction by preventing the rise of anti-tissue transglutaminase (tTG) antibodies, which are a marker of the disease.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli data-hveid=\"CAcQAg\" data-processed=\"true\"\u003e\n\u003cspan class=\"T286Pc\" data-sfc-cp=\"\" data-processed=\"true\"\u003e\u003cstrong class=\"Yjhzub\" data-processed=\"true\"\u003eImproved intestinal permeability:\u003c\/strong\u003e While not all studies showed a significant change in measured intestinal permeability (lactulose-mannitol ratio), there was evidence that the drug could prevent an increase in permeability when patients were challenged with gluten.\u003c\/span\u003e\u003cspan class=\"uJ19be notranslate\" data-wiz-uids=\"EOOE2c_1f,EOOE2c_1g,EOOE2c_1h\" data-processed=\"true\"\u003e\u003cspan class=\"vKEkVd\" data-animation-atomic=\"\" data-processed=\"true\"\u003e \u003c\/span\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"House Of Wellness UK","offers":[{"title":"Default Title","offer_id":53940564984131,"sku":null,"price":44.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0894\/1574\/5859\/files\/IMG_0969.webp?v=1777593035","url":"https:\/\/houseofwellnessuk.com\/products\/larazotide-acetate-250mcg-x-60caps-research-only","provider":"House Of Wellness UK","version":"1.0","type":"link"}